经颅直流电刺激的研究进展.pdfVIP

中国康复理论与实践2015年2月第21卷第2期 ChinJRehabilTheoryPract,Feb.,2015,Vol.21,No.2 - 171 - DOI: 10.3969/j.issn. 1006-9771.2015.02.011 ·综述 · 经颅直流电刺激的研究进展① 吴春薇，谢瑛 [摘要] 经颅直流电刺激是一种无创性大脑皮层刺激方法。本文简要回顾其起源和发展，着重综述其机制。目前观点认为，经 颅直流电刺激可能通过改变皮层兴奋性、增加突触可塑性、影响皮质兴奋/抑制平衡、改变局部脑血流、调节局部皮层和脑网联系 等途径发挥调节脑功能的作用。本文通过比较分析相关文献、总结研究结果，提出要取得理想的刺激效果，仍有待深入探讨的两 个问题，即刺激参数的选择及经颅直流电刺激与任务执行的时间关系。 [关键词] 经颅直流电刺激；机制；进展；综述 Advance of Transcranial Direct Current Stimulation (review) WU Chun-wei, XIE Ying. Department of Rehabilitation Medicine, Bei- jing Friendship Hospital Affiliated to Capital Medical University, Beijing 100050, China Abstract: Transcranial direct current stimulation is one of the non-invasive brain-stimulation techniques. Based on the introduction of the origin and development, this article gave an overview of the mechanisms emphatically, the current view is that the transcranial direct cur- rent stimulation may exert effect on neuromodulation by changing cortical excitability, increasing synaptic plasticity, impacting cortical exci- tation/inhibition balance, altering regional cerebral blood flow, modulating the activity within and between different cortical networks. In this review, clinical studies and analysis findings were compared, and then 2 problems should be discussed for ideal effects: choice of stimu- lating parameters and timing of the stimulation in relation to task performance. Key words: transcranial direct current stimulation; mechanism; advances; review [中图分类号] R454.1 [文献标识码] A [文章编号] 1006-9771(2015)02-0171-05 [本文著录格式] 吴春薇，谢瑛. 经颅直流电刺激的研究进展[J]. 中国康复理论与实践, 2015, 21(2): 171-175. CITED AS: Wu CW, Xie Y. Advance of transcranial direct current stimulation (review) [J]. Zhongguo Ka