壳聚糖负载辛可宁催化剂的制备及其在水中催化不对称Aldol反应.pdfVIP

Chinese Journal of Catalysis 36 (2015) 367–371 催化学报 2015年 第36卷 第3期 |   a v a i l a b l e  a t  w w w. s c i e n c e d i r e c t . c o m   j o u r n a l  h o m e p a g e :  w w w. e l s e v i e r. c o m / l o c a t e / c h n j c Article   Chitosan‐supported cinchonine as an efficient organocatalyst for direct asymmetric aldol reaction in water a a a b, Wenshan Zhao , Chengke Qu , Lili Yang , Yuanchen Cui * a College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, Henan, China b Key Laboratory of Ministry of Education for Special Functional Materials, Henan University, Kaifeng 475004, Henan, China   A R T I C L E I N F O A B S T R A C T Article history:   Chitosan‐supported succinic anhydride‐cinchonine (CTS‐SA‐CN) was synthesized via a two‐step Received 4 September 2014 route with succinic anhydride as the linker. The catalyst was used to promote the direct asymmetric Accepted 10 October 2014 aldol reaction between cyclohexanone and a variety of aromatic aldehydes in aqueous medium. Published 20 March 2015 Aldol adducts were obtained in excellent yields (up to 99%) and good