Gene Expression And Regulation.pptVIP

Gene Expression Expressed in the transcriptome Every eukaryotic genome contains between 5000-60,000 protein-coding genes Only a small subset of those genes are transcribed Central Dogma of Molecular Biology Expression Databases Analyses UniGene: for the comparison of cDNA libraries Goals: (1) create one unique entry for each gene, (2) collect all the ESTs associated with each gene SAGE: Serial Analysis of Gene Expression library DNA microarrays * * * Gene Expression And Regulation Bioinformatics January 11, 2006 D. A. McClellan (david_mcclellan@) ? by region (e.g. brain versus kidney) ? i