K-means and Kohonen MapsUnsupervised Clustering .pptVIP

K-means and Kohonen MapsUnsupervised Clustering Techniques Steve Hookway 4/8/04 What is a DNA Microarray? An experiment on the order of 10k elements A way to explore the function of a gene A snapshot of the expression level of an entire phenotype under given test conditions Some Microarray Terminology Probe: ssDNA printed on the solid substrate (nylon or glass) These are the genes we are going to be testing Target: cDNA which has been labeled and is to be washed over the probe Microarray Fabrication Deposition of DNA fragments Deposition of PCR-amplified cDNA clones Printing of already sy