局部晚期鼻咽癌放射治疗的研究进展.pdfVIP

156 , 徐瑾, 郝俊芳 山东省肿瘤医院放疗科, 山东 济南250117 Progress in the treatment of local advanced nasopharyngeal carcinoma X U J in, H A O J unf ang Dep artment of Radiation Oncology , Shandong Cancer H osp ital, J inan 250117, P. R. China : 分析局部晚期鼻咽癌治 [ABSTRACT] OBJECTI E: T o summa ized the ecent p o g ess in 疗的国内外研究现状和进展, 为临床治 the t eatment of local adv anced nasopha yng ea l ca cinoma. METHODS: 疗提 依据: 应用 P ubM ed 和 T he PubM ed system and CN KI dat abases w e e sea ched using the key CN K I 等数据检索系统及数据库, 以 鼻 wo ds nasopha y ng eal ca cino ma and the apy , published f om Jan. 咽肿瘤和放 射治疗 等为关键词检索 2000 to Jun. 20 10 . C ite ia of pape adoptio n: 1) Clinical st udy of na 20000 1- 201006 的相关文献, 纳入标 so pha yngeal ca cino ma including the methods, esult , and p og es 准: 1) 鼻咽癌治疗的临床试验, 包括方 ses; 2) Analysis the efficacy , side effects of adiot he apy , chemo the 法结果和进展; 2) 鼻咽癌放疗化疗及 apy and ot he the apies. A cco ding to the above c ite ia, 27 pape s 其他治疗的疗效及不良反应根据纳入 we e finally selected fo analy zed and eviewed. RESULTS: All of 标准符合分析的文献 27 篇: 各种 these diffe ent the apies make some imp ov ement . A nd most of esea 治疗方法的临床研究均取得了一定的进 ches focus o n the intensity mo dulated adiat ion the apy ( IM RT ) , IM 展, 其中调强放疗的应用使局部晚期鼻咽 RT b ings local co nt o l ates up t o mo e than 90% and obvio usly de 癌的局部控制率 90%, 且使得放疗的急 c eases the side effects compa ed with the co nv ent ional adiothe apy 慢性不良反应较常规放疗明显减轻, 但同 w ith bette spa ing of the su o unded no mal tissue, w hile IM RT need 时也对靶区的确定和勾画提出了更为严 mo e st ictly equest fo the ta get coutou ed. Co mb