不同碘营养状况与亚临床甲状腺病的相关性研究.docVIP

不同碘营养状况与亚临床甲状腺病的相关性研究 [摘要]目的 分析不同碘营养状况与亚临床甲状腺疾病的相关性，以便掌握对该类疾病的临床特点与诊治方法。方法 选取本院2011年4月至2012年4月期间于门诊接受健康体检的人群共69例，对其饮食习惯与膳食情况进行问卷调查。初步计算每日摄入体内的碘含量。对所有人的每日碘摄入量与血清中甲状腺激素的水平变化进行对比，并采用超声对其甲状腺进行检查，了解其碘营养情况与甲状腺超声改变、亚临床甲状腺疾病的关联。结果 碘摄入量与其TSH、FT3、甲状腺结节数量以及甲状腺体积均呈现明显相关，而对比碘摄入足量与碘摄入适中的人群可得，碘摄入适中的人群其TSH较碘摄入足量的人明显降低，碘摄入足量的出现亚临床甲状腺功能减退，而FT3则明显升高，差异有统计学意义(P0.05)。对比甲状腺结节的数量与甲状腺体积可得，碘摄入适中的人均明显低于碘摄入足量的人，差异有统计学意义(P0.05)。结论 碘的摄入超出正常范围，会抑制甲状腺功能，出现以亚临床甲状腺功能减退为主的功能异常症状，使甲状腺功能减退的患病率明显增加，碘过量时亚临床甲亢的患病危险减少。碘过量是亚临床甲减和临床甲减的独立危险因素。 [关键词]碘；慢性碘营养；相关性；亚临床甲状腺病 Correlation?analysis?of?the?nutritional?status?of?iodine?and?the?subclinical?thyroid?disease DengYun （The affiliated hospital of Yulin health school Department of nuclear medicine Yulin, Guangxi ,537000,） [Abstract] Objective Analysis of the correlation of different iodine nutritional status and clinical thyropathy , in order to master clinical characteristics and treatment method of this kind of disease. Method Select a crowd of 69 cases of accept the healthy check-up in our hospital during April 2011–2012 April. Survey dietary habits and diet.A preliminary calculation daily iodine content oftaken in the body. Contrast daily iodine intake and the levels of serum thyroid hormone , ultrasonic check the thyroid gland, to understand iodine nutrition situation and thyroid ultrasonic change, association of subclinical thyroid diseases. Result Iodine intake and its number of thyroid nodule, TSH、FT3 and thyroid volume significantly related to . Moderate iodine intake of TSH a significant decrease than Iodine is taken enough, Iodine is taken enough subclinical hypothyroidism, FT3 significantly increased (P0.05). Contrast the number of thyroid nodule and thyroid volume, moderate iodine is taken significantly lower than the iodine is taken enough. Conclusion Iodine is taken in the normal range ,appear subclinical hypothyroidism.Iodine excess is subclinical JiaJian and clinical JiaJian independent risk factor