乳腺增生.pptVIP

Cyclomastopathy I Review Cyclomastopathy：a kind of endocrine disease that characters in pain and lump in the breast. Corresponding disease in Traditional Chinese Medicine: nodule of breast 、phlegm of breast 、mass of breast Character of Cyclomastopathy Cyclomastopathy , also called mammary dysplasia ， is a common female mammary disease. It is a kind of abnormality in quantity and appearance of mammary glandular structure ，which is caused by accrementition and subinvolution of the mammary glandular parenchyma and interstitial substance . Main Structure of the Breast ：mammary gland fat connective tissue Cyclomastopathy The disease incidence is about 40％ during reproductive aged women , 75％ among all the mastopathia. It is the most common disease of breast。 The age of onset concludes from adolescent age to critique age，but it is more common during 25-year-old to 50-year-old ，arriving to the peak during 35-year-old to 45-year-old 。 Connection between Mammary Cystic Hyperplasia and Breast Cancer The disease is thought to cause canceration， which belongs to precancerous lesion。The chance to suffer breast cancer for the women who suffer such disease is 3～5 times more than general women ,and pathology confirms that 20％～61％ of patients suffering breast cancer may complicate with cystic hyperplasia. Etiological Factors and Pathogenesis 1、Endocrine disturbance Physiology of mammary gland Critical organ of sex hormone Main influential factors : estrogen（E）、progestogen（P） and prolactin（PRL） Estrogen enhance the growth of galactophore and fibrous tissue around Corporin enhance the development of lobules of mammary gland and gland alveolus Etiological factors and Pathogenesis During the menstrual cycle，influenced by the periodical excretion of ovarian hormone and following the generation ,excretion and exfoliation of endometria, the appearance and architecture of mammary glands also generate and involute periodically. Etiological fa