C-反应蛋白检测在感染性肺炎诊断中的应用价值.docVIP

C-反应蛋白检测在感染性肺炎诊断中的应用价值 【摘要目的临床诊断价值和意义。方法用检测通过比较分析诊断中的价值。结果病毒组的CRP含量为结论生物学诊断中来，应该加以推广。 关键词检测pplication Value of C-reactive Protein test in the Diagnosis of Infectious Pneumonia [Abstract] Objective To analysis the clinical value and significance of detect C-reactive protein (CRP) in the diagnosis of infectious pneumonia. Methods Since 2009, the department of respiratory medicine in our hospital had admissioned 342 cases of patients with infectious pneumonia, according to their type of infection is divided into 2 groups, 170 cases of bacterial pneumonia group and 172 cases of viral pneumonia group. Use automatic nephelometric assay to test C-reactive protein levels in patients before and after treatment. According to the data obtained through comparative analysis to evaluate the value of CRP test in the diagnosis of infectious pneumonia. Results Bacterial pneumonia group CRP levels was (80.7 ± 50.4) mg / L, viral pneumonia group CRP levels was (10.9 ± 4.2) mg / L, the difference was statistically significant (P 0.05); the CRP levels in bacterial pneumonia group change significantly before and after treatment, while in viral pneumonia group the CRP levels did not change significantly before and after treatment. Conclusion Serum CRP protein levels can be used in the biology diagnosis in patients with bacterial pneumonia, and should be promoted. [Keywords]C-reactive protein; Detection; Infectious Pneumonia; Diagnostic value; 肺炎是肺部的炎症反应，是由于感染，感染原因包括细菌性感染和病毒性感染，也包括一些其他微生物、药物感染和其他情况如自身免疫系统疾病。对其常规诊断通常是用X射线和痰液培养[1] [2]。CRP是由肝脏合成的一种急性期蛋白。为了响应感染的发生或组织的炎症反应，CRP受细胞因子的刺激而迅速产生，尤其是白介素-1、白介素-6以及肿瘤坏死因子。近年来发现，生物标志物检测，在感染性肺炎的诊断中能达到理想的效果[3] [4]。CRP在感染性疾病的诊断中也显示了一定的优势本研究旨在探讨CRP含量的检测在感染性肺炎临床诊断中的应用价值和意义，现将研究结果汇报如下： 1.一般资料 1.1研究对象 抽取自2009年3月以来我院接诊的感染性肺炎患者342例（已经过血常规、CRP和血清学检查确诊），男性患者214例，女性患者128例按照其感染类型分为细菌性肺炎组170例，其中男性患者108例，女性患者62例，年龄在26-83岁，平均年龄（50.4±7.3）岁；病毒性肺炎组172例，其中男性患者106例，女性患者66例，年龄在26-86岁，平均年龄（51.9±6.0）岁。因此具有可比性。 1.2检测方法 CRP检测采用散射免疫比浊法，仪器为 Beckman IMMAGE 800全自动分析仪，试剂为仪器配套试剂正常参考值1