a rapid determination method for ethylenethiourea in potato and cucumber by modified quechers – high performance liquid chromatography–tandem mass spectrometry论文.pdfVIP

Food Chemistry 138 (2013) 1355–1359 Contents lists available at SciVerse ScienceDirect Food Chemistry journal homepage: www.elsevier .com/locate/foodchem Analytical Methods A rapid determination method for ethylenethiourea in potato and cucumber by modified QuEChERS – High performance liquid chromatography–tandem mass spectrometry Li Zhou a, Xiaoliang Liu b, Shu Kang a, Fengzu Zhang a, Canping Pan a,⇑ a Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China b Institute of Pesticide Environmental Toxicology, Guangxi University, Nanning 530000, China a r t i c l e i n f o a b s t r a c t Article history: A rapid and sensitive analytical method for the determination of ethylenethiourea (ETU) in potatoes and Received 3 May 2011 cucumbers is developed. This method employs modified QuEChERS followed by high performance liquid Received in revised form 14 April 2012 chromatography–tandem mass spectrometry (HPLC–MS/MS) analysis. ETU was extracted by alkaline ace- Accepted 8 November 2012 tonitrile (containing1%NH .H 0), separated on a ZIC-pHILIC column, confirmed by multiple reaction mon- 3 2 Available online 17 November 2012 itoring (MRM) mode with electrospray ionisation source. This modified procedure showed satisfactory recovery (90.6–103.5%) fortified at the range of 0.005–0.05 mg kg1 with relative standard deviation Ke