气道支气管曲霉病1 例报告及文献复习.pdfVIP

2008 11 20 8 6 Chin J Inf ect Chemother, Novem ber1 2008, Vol1 8, No1 6 437 # # 1 曹鄂洪, 施 毅, 赵蓓蕾, 宋 勇, 肖鑫武, 肖永营, 徐小勇 : 1 1 , , , , 2 4 , , : ; ; ; : R3 79 . 6 : A : 10 09- 770 8( 20 08) 0 6- 0437- 04 Tracheobronchial aspergillosis : one case report and literature review CA O E-hong , SH I Yi, ZH A O Be i-le i, S ON G Yong , X IA O X in-w u, X IA O Yong-y ing , X U X iao-y ong . (D ep a tment of R esp i atology , Cl inical School of Medical College, N anj ing Univ e sity , N anj ing Gene al H osp ital of P LA , N anj ing 210 002, China) Abstract: Objective T o explore the clinical manife tation , diag no i and treatment of airway inva iv e a per gillo i . Methods T he clinical manife tat ion , bro ncho copy biop y and hi tolog ical analy i of one ca e of airway inva ive a perg illo i wer e re- v iewed. Results T he clinical manife tat ion included product ive cough, hemopty i and dy pnea. A big neofor matio n wa pr o- t ruding into the lumen under fibreoptic broncho cope. Patholog ic ex amination found A sp e g il lus pecie invading t hr ough br on- chial wall. T he patient w a cur ed after treatment with itr aco nazole for 2 4 w eek . Conclusions T he airway inva ive a perg illo i i char acterized by the pre ence of A sp e g illus or gani m inv ading to the airw ay ba ement membrane. Br oncho copy i very im- portant for accurat e diag no i . Itr aco nazole i one of the efficaciou and afe agent in the tr eatment of airway inv a ive a perg il- lo i . Key words: Airw ay; A perg illo i ; Fibr eoptic bro ncho copy; Itraconazole T 37. 6 e , R 16 / m