1921例眼眶肿瘤的组织病理分类.docVIP

1921例眼眶肿瘤的组织病理分类HistoPathologieClassifieation of 1921OrbitalTumors 倪连 马小葵 上海医科大学眼耳鼻喉科医院眼科病理室，上海200031 ChuoNi，XiaokuiMa Eye and Ear Nose Throat Hospital,Shanghai Medical University,Shanghai 200031 China. 目的:对本院收检的1921例眼眶肿瘤进行组织病理分类，对有代表性的肿瘤，容易误诊的肿瘤及一眼眶的罕见肿瘤进行讨论。 方法:对本文包括的所有病例及病理切片进行复查，疑难及争议病例进行讨论，并采用特殊染色，免疫组化等手段加以证实。 结果:恶性肿瘤的前5位:泪腺恶性肿瘤138例(32%)，泪囊恶性肿瘤112例(26%)，横纹肌肉瘤65例(15%)，淋巴肉瘤56例(13%)，血管外皮肉瘤31例(7环)。良性肿瘤前5位为:窦性血管瘤411例(36%o，皮样囊肿152例(13纬)，泪腺良性混合瘤150例(13%)，炎性假瘤129例(n%)，神经鞘瘤92例(8%)。眼眶罕见肿瘤有腺泡型软组织肉瘤，软骨肉瘤，色素性视网膜原基瘤，内胚窦癌等。 结论:本文对眼眶肿瘤的组织病理分类，比较完善地反映了各类肿瘤在眼眶的发病情况。眼科学报1995;11:101一1040 关键词:眼眶肿瘤 泪腺肿瘤 血管瘤病理学 Purose:The retrospeetive study15 undertaken to determine the histopathologie types of sPaee一oeeuPying lesions of the orbitin1921eases examined between 1953-1992 at the Eye Pathology laboratory of Shanghai Medieal University. Methods:The authors reviewed old diagnostie pathologie slides on fileineluding HEstainaswellass浓eialstains，ifavailable，foralltheindeterminateeases.Newly PrePared immuno histoehemiealstainsaremadefortheeontroversialeases tohelpdiagnosis.SomeslidesarediseussedanddiagnosedbyPathologySlide Meetingo王theShanghaiSurgiealPathologySoeiety.Caseswithdiagnosisnota-greeduponbythepathologymeetingareexeludedfromthisstuldy. Results:The5leadingmalignantorbitaltumorsaremalignantlaeritnalglandtu-mors(138eases，32%)，malignantlaerimalsaetumors(112eases，26%)，rhab-domyosareomas(65eases，15%)，lymphosareomas(56eases，13%).andmalig-nanthemangioperieytomas(31eases，7%).The5leadingbenig，:orbitaltumors areeavernoushemangionas(411eases，36%)，dermoidCysts(152CaseS，13%)，benignmixedtumors(150eases，13%)，inflamrnatorypseudotumosr(129eases，11%)，andsehwannomas(92。ases，8%).Raretumorsoftheorbitinel、ldealve-olarsofttiss、一esareoma，ehondrosareoma，mesenehymalehondrosareoma，syn-ovialsareoma，gianteelltumor，granularmyoblastoma，yolksaetumor，and retinalanl age tumor. Conelusion:Thisstudy，121agreemantwithotherreportsofthestaties study of the orbital tumors demonstrates he Prevale一ee of hemangiomas，laerimalgl