低分子肝素在人工肝脏中临床应用地研究.pdfVIP

低分子肝素在人工肝脏中临床应用的研究 王海霞江元森谢傻强李学傻 邓友庄鹛张绍全姚集鲁 中山大学附属第三医院人工肝研究室(广州510630) I箍要)目的探讨低分子肝素和普通肝素在人工肝脏中的疗效与安全性。方法对84例 人工肝治疗慢性重型肝炎临床资料进行回顾性分析．结果23例普通肝素组(standard heparin． 血：61例低分子肝素组(10w 浆分离器的凝血情况均为I-u级凝血．两组均无严重出血情况发生．LMWH组在改善凝血酶 原时间及黄疸消退方面优于sH组(p如．05)。结论低分子肝素具有良好的抗凝结果，能保证 血浆置换的顺利进行，同时不易加重出血，较适用于肝功能衰竭患者。 I关键词】低分子肝素普通肝素抗凝人工肝重型肝炎 To theclinical low of molecular on study application weightheparin artificialliver Toevaluatethe and of [Abstract]Objective standard low efficacysafety heparin(SH、and molecular artificialliver．Methodsdata weigIltheparin(LMWH)in Clinical with of84patients chronicSeVere treatmentartificialliver were hepatitis by supportsystemanalyzed retrospectively． In ResultsSH of30membrane w笛IIl and3of30 groups．8 plasmaseparatordegree coagulation of was WasIV LMWH membrane inI-II degree coagulation．Ingroup，all plasmaseparator degree two Wasnosevere between coagulation．Therehemorrhage symptom groupimprove groups．LMWH timeandtotalbilj^lbinbetterthanSH Lowmolecular prothrombin