本科化学毕设计.docVIP

目 录 1. 前言························································································································2. 实验部分 ···········································································································2.1 仪器与试剂·········································································································· 3-取代香豆素的合成方法·················································································· 2.3 产物的表征·········································································································3. 实验结果与讨论···································································································3.1 实验讨论··············································································································3.2 实验结论 ············································································································4. 参考文献············································································································6 ··················································································································8 FeCl3催化的串联反应合成香豆素类化合物 XXX （XX师范大学 化学与材料科学学院 芜湖 241000） 摘要： 关键词–Catalyzed Efficient Multicomponent Reaction Synthesize Coumarin Derivatives Jinlei （College of Chemistry and Materials ScienceAnhui normol university, Wuhu, 241000, China） Abstract: We have developed an efficient FeCl3–Catalyzed method for the synthesis of the coumarin derivatives.The protocol uses iron(Ⅲ)chlorine as the catalyst,and furnished the expected product in good to satiesfied yields by a two-component reaction of salicylaldehyde and malononitrile derivatives in ethanol absolute at 70℃ for 8h in the presence of coumarin.This novel synthetic protol is selective,effcient and general.A plausibe mechanism for the progress is proposed.And we also have a correspondent reseach on Na2CO3 catalyst when the yield is better than FeCl3.The structure of all the