Treatment Strategies for Huge Central Neurocytomas.pdfVIP

JHuazhongUnivSciTechno1M『edSci1 DOI10．1007／s11596．015．1397—2 35(1)：105_110，2015 105 TreatmentStrategiesforHugeCentralNeurocytomas Zhong．weiXIONG(熊忠伟)，Jian-jianZHANG(章剑剑)，Ting—baoZHANG(张庭宝)，Shou-jiaSUN(孙守家)， Xiao．1inwu(吴小林)，HapWANG(王 昊)，ChapYOU(游 超)，YuWANG(王 煜)，Hua-qiuZHANG(张华楸)， Jin—capCHEN(陈劲草) DepartmentofNeurosurgery,Ton~iHospitalTong／iMedicalCollege,HuazhongUniversityofScienceandTechnology,Wuhan 43003~China ：DepartmentofNeurosurgery,ZhongshanHospitalofHubeiProvince,Wuhan430032,China ◎HuazhongUniversityofScienceandTechnologyandSpringer-VerlagBerlinHeidelberg2015 Summary：Centralneurocytomas(CNs)，initiallyasymptomatic，sometimesbecomehugebeforedetec． tion．Wedescribedandanalyzedtheclinica1．radiologica1．operationalandoutcomedataof13casesof hugeintraventricularCNs，naddiscussedthetreatmentstrategiesinthisstudy．A11hugeCNs(=13)in oursutdywerelocatedinbilaterallateralventriclewithdiameter 5．0cm andhadabroad—basedat． tachmenttoatleastonesideoftheventriclewal1．Al】patientsreceivedcraniotomytoremovethetumor through transcallosalortranscorticalapproachnad CNswereoftypicalhistologicandimmunohisto— chemica1features．AdJuvnattherapiesincludingconventionalradiationtherapyfRT)orgammaknifera— diosurgery(GKRS)werealsoperformedpostoperatively．Transcallosalandtranscorticalapproaches wereusedin8and5patients，respectively．Twopatientsdiedwithinonemonthafteroperationand3 patientswithgrosstotalresection(GTR)wereadditionallygivenadecompressivecraniectomy(DC) nad／orven仃iculoDeritonea1shunt(VPS)asthesalvagetherapy．SixpatientsreceivedGTR(+RT)and7 patientsreceivedsubtotalresection(STR)(+G