治未病理论在复发型寻常型银屑病防治中的应用的研究.doc

结论：治未病理论指导下，经过既病防变的综合干预和病后防复的主动预防，复 发型寻常型银屑病缓解症状和延长缓解期均有显著改善，防治效果理想。  关键词  银屑病；治未病；体质；认知行为干预；缓解期 Application of “Theory of Preventive Treatment Of Disease” in prevention and treating of relapsing psoriasis vulgaris Specialty：Dermatology,Surgery of TCM Tutor：Professor Du Xixian Author：Wang Jianqing Abstract Objective: to verify the effaction of comprehensive intervention on relapsing psoriasis vulgaris under the “Theory of Preventive Treatment Of Disease”of Traditional Chinese Medicine. Methods: Clinical study is divided into two parts,the first: to pre-survey the patients of relapsing psoriasis: Summarying the triggers of recurrence or worsening of psoriasis , the condition, treatment, prevention an constitution of patients. The second:Process is divided into two phases,the first is to prevent the disease developing:86 patients of relapsing psoriasis vulgaris were divided into 2 groups, experimental group 44 patients and control group 42 patients,both employing the oral chinese herbs “Clearing Heat and Removing Damp Drinking” and topical ointment of long zhu,1-2 times/d.12 weeks. In addition to medcine, experimental group received cognitive-behavio- ur therapy and relaxation training at the same time.PASI score need to count at begnning,4th week,8th week,12th week,and measure blood serum level of VEGF,TNF-α and IL-10 and ratio of TNF-α between IL-10 at the begnning and end. The second stage , preventing relapse:27 patients which have finished the first stage prevention and treatments employed the oral chinese herbs “Yu Ping Ying Xing Fang”,3 weeks,and continued cognitive-behaviour therapy and relaxation training at the same time.Patients were Followed-up from 15 months to 2 years, counting the remission times of psoriasis vulgaris to verify the effaction of intervention by compaing of this time with last time and the longest remission times. Results: PASI score comparying between 2 groups in the first phase:It is no significant at begnning,4th week,8th week(P﹥0.