芪参益气滴丸联合西药对冠心病心绞痛气虚血瘀证患者疗效的影响.pdfVIP

现代药物与临床 Drugs Clinic 第 27 卷 第 4 期 2012 年 7 月 • 389 • 芪参益气滴丸联合西药对冠心病心绞痛气虚血瘀证患者疗效的影响 1 2 高 晟 ，周 静 1. 天津市南开医院，天津 300100 2. 天津中医药大学第一附属医院，天津 300193 摘 要：目的 通过给予冠心病心绞痛气虚血瘀证患者芪参益气滴丸及西药治疗，探讨其疗效及对中医症状的影响。方法 将 59 例冠心病心绞痛气虚血瘀证患者随机分为西药组（29 例）和西药＋中药组（30 例）。西药治疗：参照美国心脏病学院/美 国心脏学会/美国医师学院联合议定的冠心病心绞痛诊断及治疗指南；中药治疗：给予芪参益气滴丸 0.5 g，tid ，治疗 60 d 。 观察治疗前后心绞痛疗效、硝酸甘油停减率及中医症状评分变化。结果 治疗后，西药＋中药组心绞痛总有效率及硝酸甘油 停减率高于西药组，但 2 组比较无统计学意义（P ＞0.05 ）；治疗后，2 组胸痛、胸闷症状明显改善，2 组与治疗前比较有显 著差异性（P ＜0.01 ）；西药组气短、乏力、心悸、自汗、面色少华症状无明显改善，与治疗前比较无差异性（P ＞0.05 ）。西 药＋中药组气短、乏力、心悸、自汗、面色少华症状明显改善，与治疗前比较有显著差异性（P ＜0.01 ），西药＋中药组中医 症状的改善优于西药组，且有显著差异性（P ＜0.01 ）。结论 联合应用芪参益气滴丸及西药能有效地改善冠心病心绞痛气虚 血瘀证患者的疗效及中医症状，值得临床推广。 关键词：芪参益气滴丸；冠心病；心绞痛气虚血瘀证；中医症状 中图分类号：R286.02 文献标志码：A 文章编号：1674 - 5515(2012)04 - 0389 - 04 Efficacy of Qishen Yiqi Dripping Pills with western medicine on deficiency of vital energy and blood stasis of patients suffered from angina pectoris 1 2 GAO Sheng , ZHOU Jing 1. Tianjin Nankai Hospital, Tianjin 300100, China 2. First Teaching Hospital of Tianjin University of TCM, Tianjin 300193, China Abstract: Objective To investigate the effect of Qishen Yiqi Dripping Pills (QYDP) with western medicine on the deficiency of vital energy and blood stasis (DVEBS) of patients suffered from coronary heart disease (CHD)-caused angina pectoris. Methods Fifty-nine patients with DVEBS of CHD-caused angina pectoris were randomly divided into two groups, they are western medicine (WM, 29 patients) group and western + traditional Chinese medicines (WTCM, 30 patients) group. The therapy of WM group was in accordance with the guideline for diagnose and therapy of CHD-caused angina pectoris by American College of Cardiology (ACC)/American Heart Association (AHA)/American College of Physicians (ACP). Th