不同茶类多糖对实验型糖尿病小鼠治疗作用的比较研究.pdfVIP

茶 叶 科 学 2002 22 2 160— 163 Journal of Tea Science 文章编号 1000 — 369X 2002 02 — 0160 — 04 不同茶类多糖对实验型糖尿病小鼠治疗作用的比较研究 倪德江, 谢笔钧, 宋春和 (华中农业大学茶学专业, 湖北 武汉430070) 摘要 比较绿茶 乌龙茶 红茶 黑茶 白茶茶多糖 TPS 对四氧嘧啶诱导的糖尿病 DM 小鼠模型的降血 糖效果 结果表明 在所设定的低 中 高剂量 200 mg/kg.d 400 mg/kg.d 800 mg/kg.d 下 各种茶叶TPS 对 DM 小鼠都有显著或极显著的降血糖效果 其中绿茶具有明显的量效关系 而其它茶类量效关系不明显 在 低 中剂量下 乌龙茶 红茶 黑茶 白茶TPS 降低血糖的作用明显优于绿茶TPS 但在高剂量下差异不明显 TPS 经木瓜蛋白酶水解后的降血糖效果优于未经水解的TPS 灌胃酶解TPS 的DM 小鼠血糖值较灌胃非酶解TPS 的降低 13.79% 已接近正常小鼠血糖水平 关键词 生物化学 茶多糖 糖尿病 血糖 中图分类号 Q538 文献标识码 B Comparative Studies of Tea Polysaccharides from Different Kinds of Tea on Diabetic Mice NI De-jiang , XIE Bi-jun , SONG Chun -he (Huazhong Agriculcural Universit y, Wuhan 430070 , China) Abstract: To compare the effect of tea polysaccharides TPS from green tea extracts GTE Oolong tea extracts OTE black tea extracts BTE dark green tea extracts DGTE and white tea extracts WTE on blood glucose BG of alloxan-induced diabetes animal model. Results showed that b lood glucose decreased considerably after one week of experiment. There was obvious relationship between the role in reducing BG and the dose of GTTPS . The effect of OTTPS BTTPS DGTTPS and WTTPS in reducing the blood-glucose was better than that of GTTPS under low and moderate doses. However, there were no obvious differences between various treatments under high dosage. Being hydrolyzed by papain the effect of TPS in reducing BG was better. The blood-glucose value in DM mice ingested the enzyme-decomposed TPS via gastrogavage was 13.79% lower than that ing