应用抗生素对口腔酸碱环境影响.pdfVIP

8·90 · Chin J Nosocomiol Vol. 12 No. 12 2002 应用抗生素对口腔酸碱环境的影响 田 　耘, 王宝佳 , 吴晶婷 , 杨 　明 , 陈 　敏 (解放军第 44 医院 , 贵州 贵阳 550006) 摘要 : 目的 　了解不同抗生素对口腔酸碱环境的影响。方法 　分别对应用包括氨苄西林、美洛西林、头孢噻啶和 妥布霉素的 191 名患者的口腔 p H 值进行检测并进行比较分析 ,利用广泛试纸和精密试纸在每日早晨给药前、给 药后和下午给药前及给药后进行测定。结果 　不同抗生素应用后 ,患者口腔p H 值均有不同程度的升高 ,但升高 的快慢和幅度不同 ,应用青霉素类的抗生素氨苄西林和美洛西林的患者在给药后 , 口腔p H 值升高较快 ,而头孢 菌素类的头孢噻啶和氨基糖苷类的妥布霉素给药后 ,患者口腔p H 值上升较缓慢 ,头孢噻啶组则在第 1 日下午给 药后测试时口腔 p H 值上升最明显。结论 　应用抗生素会对口腔酸碱环境产生一定的影响。 关键词 : 抗生素 ; 口腔; p H 值 中图分类号: R181. 3 + 5 　　文献标识码 : A 　　文章编号 : (2002) Influence on Oral Acidbase Environment by Applying Antibiotics TIAN Yun , WAN G Baojia , WU Jinting , YAN G Ming , CHEN G Min ( ) Depart ment of N ursin g , the 44 th Hospital of PL A , Guiyan g 550006 , China Abstract : OBJECTIVE To understand the influence on acidbase conditions in the oral cavities after using antibiotics. METHODS The changes in oral p H level were tested and analysed in 191 patients given ampicillin , mezlocillin , cefalori dine and tobramycin before and after giving drugs in the morning , and before and after giving drugs in the afternoon. RESULTS There were differences in p H value of patients using different antibiotics. Oral p H value of the patients with ampicillin and mezlocillin rose faster than that with cefaloridine and tobramycin. The p H value of patients with cefalori dine went up remarkably after giving drug in the afternoon of the first day. CONCL USIONS Oral acidbase environment was affected by using antibiotics. Key words : Antibiotic ; Mouth ; p H Level 　　口腔内酸碱度受多种因素影响 ,不同年龄、不同 腔内酸碱状况