海南地区135例胆石病的特点和临床流行病学调查_王海东.pdfVIP

《海南医学》2002 年第 13 卷第 9 期 流行病学 海南地区 135 例胆石病的特点和临床流行病学调查 ( ) 海南省人民医院肝胆外科 海口　570311 　王海东 　郑进方 摘要 　目的　探讨海南地区胆石病的临床流行病学特点 ,及其影响因素 。方法 　本文对海南地区 135 例胆石 病患者进行回顾性流行病学因素调查 ,对术中取得的胆石进行化学成分测定 。结果 　胆管结石 占51. 9 % ,胆固醇 类结石占65 . 9 % 。城镇居民、高脂饮食及肥胖者的胆囊结石发病率高 ,而农村居民、低脂饮食者的胆管结石发病率 ( ) ( ) 高 。胆管结石患者的胆汁细菌培养阳性率 65 . 7 % 高于胆囊结石患者的胆汁细菌培养阳性率 18. 5 % 。结论 　海 南地区胆石的分布部位胆囊结石与胆管结石比例接近 ;类型以胆固醇类结石为主 。职业 、生活条件 、饮食习惯等因 素与胆囊结石和胆管结石的发病率有关 。高脂饮食及肥胖是造成胆囊结石的主要因素 ,而低营养 、低脂饮食与胆管 结石的形成有关 。反复胆道细菌感染在胆管结石形成中可能起重要作用 。 关键词 　胆结石 　化学分析 　流行病学 Clinical epidemic investigation in gallstone patients in Province of Hainan . WAN G Haidong , ZHEN G J inf ang . Dep artment of Hep atobiliary S urgery , Hainan Province people ’s Hospital , Haikou 570311 Abstract Objective : To investigation the epidemic characters of gallstone in gallstone patients. Methods : 135 patients with gallstone underwent operation from September 1991 to December 1997 . The factors of clinical epidemic were analyzed retrospective ly ,and the elements of gallstone were examined . Results : 51. 9 % of cases were hepatolithiasis and cholesterol stone was about 65 . 7 %. The incidence of gallstone were higher in such patients as city residents , high lipid diet and with fat ,whereas The incidence of hepatolithiasis were higher in such patients as in rural areas ,lower lipid diet . Positive rate of biliary bacterial culture was 65 . 7 % in hepatolithiasis paitents ,w