血管外膜在血管病变中作用地研究进展_葛小丽.pdfVIP

# 950# 辽宁中医杂志 2010年第 37 卷第 5期 , (河北以岭医药研究院, 河北石家庄 050035) : 外膜是血管壁的重要组成部分近期研究表明血管外膜的功能不仅局限于外膜, 而且亦可影 中膜和内 膜外膜在血管病变中起着重要作用血管外膜具有强大的神经- 内分泌- 免疫调节系统, 对血管的结构和功能有重 要影 ; 血管外膜具有丰富的滋养血管,血管内的血流动力学变化可导致新生血管的生成,并且和多种疾病有关; 血管外 膜的成纤维细胞的增殖在血管阻塞性疾病的发生发展中扮演着重要的角色从血管外膜的结构和功能以及外膜在血管 病变中的作用两 个方面进行了阐述以期为血管病变的治疗提供新靶点 : 外膜; 结构; 功能;血管病变 : R54 : A : 1000- 1719( 2010) 05- 0950- 03 T he R esearch P rogress of Adventitia in V ascu lar D isease GE X iao-li, LIAN G Jun-qing (H ebei YiL ing P harm aceuticalR esearch Institute, hij iazhuang 050035, H ebe,i China) A bstrac t: Adventitia is an mi portant part of the vesselwal.l Recently, the study indicates that the function ofVascular adven- titia is not only lmi ited to the adventitia, but also can affect themembrane and the endometrial. adventitia plays an mi portant role in vascular disease. The adventitia has erve- endocrine- mi mune- conditioning systems, which play an mi portant mi pact on structure and function ofVascular; theAdventitia is rich in blood vessels and intravascular hemodynam ic changesmay lead to an- giogenesiswhich lead tomany diseases; V ascular adventitial fibroblasts proliferation play an mi portant role in the occurrence and development of vascular occlusive disease. In this test, we expound wt o aspects: one is the the adventitia structure and function; the other is the role of adventitia in vascular disease. K ey w ord s: adventitia; structure; function; vascular disease , 151 6% [ 3] ,, , . 1314% 1217% ,, [ J]. ,