从胰腺受累部位探讨急性胰腺炎发病机制.pdfVIP

·571． 宣墅堑兰塑壁疸堂盘查!Q!!生!旦笙垫鲞笙鱼塑垦!尘!鱼!!!!竺!堡!!!旦!P!!!!!』!!!Q!!!!!!：!Q!塑!：鱼 从胰腺的受累部位探讨急性胰腺炎的发病机制 冯红霞’，赵 琦’，刘 莉2，马 勇3 1．聊城市人民医院脑科分院，山东聊城252000；2．潍坊医学院附属医院；3．聊城市人民医院cT室 【摘要】 目的 分析胰腺炎时胰腺的常见累及部位及病凶，初步探讨急性胰腺炎的发病机制。方法 月在我院住院的408例急性胰腺炎患者的累及部位及病岗作【口]顾分析。结果74．0％患者为高脂血症导致的胰腺炎；100％胰腺 炎患者胰腺尾部受累．83．8％患者为胰腺尾部或体尾部受累。高脂m症性胰腺炎以体尾部或头体尾部问时受累为主，胆源性胰腺 胰腺炎的受累部位提示胰腺炎的发生除胰酶激活引起自身消化之外，胰腺微循环障碍造成胰腺实质缺m缺氧亦是重要的发病机 制。对于胰腺炎的治疗除了抑制胰液分泌，抑制胰酶活性之外，改善胰腺微循环亦足非常重要的措施。 【关键词】 急性胰腺炎；生化分析；cT 中图分类号：R576 文献标识码：A 文章编号：1006—5709(2叭1)06—057l一02收稿日期：2010．1l一2l The in with manifestationof acute computedtomographypatients pancreatitis FENG Hongxial，zHAOQil，I．IULi2，MAYon93 of of Aml— 1．DepartmentGastroenterology，Liao(：hengPepole’sHospitalShandongProvince，Liaocheng252000；2．The iated of Medical of HospjfalWeifang College；3．LjaochengPepole’sHospitalShandong，China To of maninstationof 【Abstract】objectivestudypathogenesispancreatitisthrough computed Clinicaldataof of408 withacute was computedtomographypatients pancreatitisanalyzed examinationweremoreindicatiVeof of andtailinmostof whilein— Computedtomographic injurypancreasbody patients of headwasnot of andta订in withmildacute and common．Injury jurypancreas pancreasbody patients pancreatitishy- were in withsevereacute was perlipidemia-inducedpancreatitiscommon；whoIepancreaspatients pancreatitisdamaged． ConclusionPancreaticmicrocirculationisthe ofacute besidesself．di— dysfunctionimportantpathogenesispan