色谱技术在牛奶中抗生素残留检测方面的应用.pdfVIP

※专题论述 食品科学 2010, Vol. 31, No. 01 287 翟宗德，曹程明，葛 宇，周耀斌，张 辉，宁啸骏 (上海市质量监督检验技术研究院，上海 200233) ：由于近期发生的三聚氰胺奶粉事件，目前牛奶及奶制品的安全问题是国家及社会关注的焦点问题之一。 因而奶制品中有毒有害物质检测技术也成为当前食品检测领域的研究热点。针对抗生素残留问题是牛奶及制品安全 方面的一大突出问题，本文以抗生素类别为划分综述了近年来色谱技术及其与质谱联用分离分析技术在奶制品中抗 生素类残留检测中的应用，主要包括气相色谱、液相色谱及色谱质谱联用技术等。 ：色谱；质谱；牛奶；抗生素 A Review of Application of Chromatographic Techniques to Determination of Antibiotic Residues in Milk and Related Food Products ZHAI Zong-de ，CAO Cheng-ming ，GE Yu ，ZHOU Yao-bin ，ZHANG Hui ，NING Xiao-jun (Shanghai Institute of Quality Inspection and Technical Research, Shanghai 200233, China) Abstract ：Nowadays, the safety of milk and related food products has become one of the health concerns of the country and even the world due to the melamine milk powder incident that broke out in China in 2008. As a consequence, the development of analytical techniques for hazardous and toxic substances in milk and related food products is becoming one of the hot research interests. In order to provide a useful guidance for effectively solving the antibiotic residue problems in milk and related food products, this paper reviews the applications of chromatographic (gas, liquid) and chromatographic-mass spectrometric tech- niques to the determination of antibiotic residues in milk and related food products according to antibiotic kind. Key words ：chromatography ；mass spectrometry ；milk ；antibiotic 中图分类号：TS207.53 文献标识码：A 文章编号：1002-6630(2010)01-0287-05 近年来，国内外有关食品安全的负面新闻不断， 药不当；违反国家规定把抗生素作为奶牛饲料添加剂使 社会对食品安全的呼声也越来越高，食品安全问题是关 用；使用未经彻底清洗和消毒挤奶工具和贮奶设备造成 系经济民生的重大问题。在众多食品安全的热点问题 牛奶中抗生素的污染；在牛奶中掺杂各种抗生素防止牛 中，牛奶及相关产品与人们的生活息息相关，牛奶安 奶酸败等原因[ 2 ] 。近年来，由