Nutrients that prevent Cancer.ppt

In research studies, calcium has been shown to play a preventative role in colon cancer and breast cancer, especially breast cancer in pre-menopausal women. * The exact mechanism by which calcium prevents cancer is unclear. At the biochemical level it is clear that calcium binds to both bile and fatty acids in the gastrointestinal tract to form insoluble complexes. Because the calcium is bound to the acids, it reduces the ability of the acids to damage cells located in the lining of the colon. Calcium also acts directly in reducing cell proliferation in the lining of the colon. Both mechanisms are thought to contribute to calcium’s prevention of cancer. * A strong relationship between calcium intake and colorectal cancer risk was found in the participants of the Nurses’ Health Study and Healthy Professionals Follow-up study conducted by _________ and published in _______. In this study, researchers analyzed 135,000 men and women and found that the people who consumed 700 mg of calcium per day reduced their risk of colorectal cancer by 35-45% when compared to people with intakes of 500 mg of calcium per day or less. This effect was only recognized in the distal area of the colon, and intakes showed no effect on the proximal colon. * Another study done by the National Institutes of Health-American Association of Retired Persons Diet and Health Study which was published in _______ by ________, showed that high intakes of total calcium, dietary calcium, and calcium supplements were associated with 20% lower risk of colorectal cancer among men and 30% lower risk among women. * A study published in ______ by _______examined women living in Iowa. This study compared 34,000 women divided into two groups. One group consumed approximately 1280mg of calcium or more a day and was compared to a second group of women with calcium intakes of 800 mg per day or less. Total intakes in the two groups were from both diet and supplements. The group of women who consumed the