Organometallic Chemistrybetween organic and inorganic.ppt

Organometallic Chemistry Organometallic Chemistrybetween organic and inorganic Course Roadmap A real example: the Monsanto Acetic Acid process Introduction: what is organometallic chemistry, and why should you care? Electron counting: the basis for understanding structure and reactivity An overview of Main-group and Transition metal chemistry Main group metal chemistry and Umpolung Intermezzo: characterization of organometallic compounds Transition metal chemistry: overview of common ligands Ligand substitution Insertion and elimination Oxidative insertion and reductive elimination More exotic steps Your own presentations Applications in catalysis Example: Acetic Acid synthesis Acetic acid is an important industrial chemical. The traditional synthesis uses bio-oxidation of ethanol obtained via fermentation: C6H12O6 ? 2 C2H5OH + 2 CO2 C2H5OH + O2 ? CH3COOH + H2O This is not a clean and efficient process! Industrial acetic acid synthesis: CH3OH + CO ? CH3COOH Catalyzed by a rhodium complex. Acetic Acid synthesis Moderately complexcatalytic cycle: Acetic Acid synthesis This cycle is knownin considerable detail: To understand it,you need to be familiarwith electron countingand commonreaction types What is organometallic chemistry ? Strictly speaking, the chemistry of compounds containingat least one metal-carbon bond. Metal hydrides are often included, H being considered as the smallest organic group (as in propyl, ethyl, methyl, hydride). Metal-carbon bonds are often formed temporarily or potentially, so in practice many compounds are includedthat do not actually contain metal-carbon bonds. Why should you care ? Organometallic chemistry is the basis of homogeneous catalysis, which is the method of choice for clean and efficient synthesis of fine chemicals, pharmaceuticals and many larger-scale chemicals. Many plastics (polythene, polypropene, butadiene rubber, ...)and detergents are made via organometallic catalysis. Organometallic chemistry is also