慢性肝病患者自评量表的应用评价研究.pdfVIP

2010年 6月第 17卷第 6期 中国中医药信息杂志 ·13· 慢性肝病患者自评量表的应用评价研究 刘慧敏,刘绍能,刘 震,陶夏平 (中国中医科学院广安门医院,北京 100053) 摘要：目的 评价慢性肝病患者自评量表的信度、效度及反应度。方法 以慢性乙型肝炎、慢性丙型肝炎、酒 精性肝炎、脂肪性肝炎、肝硬化代偿期为研究对象,应用我们以往研究编制的慢性肝病患者自评量表进行测评。共纳 入患者 104 例,与 51 例正常人对照,进行信度、效度、反应度分析,并对慢性肝病患者与正常人、慢性乙肝患者与其 他肝病患者进行对比分析。结果 该量表总体克朗巴赫α系数为 0.915,总体 Guttman 折半系数 0.703；该量表 KMO 统计量为0.783,Bartlett球形检验卡方值1801.149(P ＜0.001),主成分因子分析方法提取特征根值＞1的8个公因 子,累计贡献率为69.636%；以 t检验方法分别分析慢性肝病患者与正常人、慢性乙肝患者与其他肝病患者量表总分,P 值分别为0.000、0.413。结论 该量表有较好的信度、效度及反应度,可作为慢性肝病患者临床疗效的评价工具。 关键词：慢性肝病；自评量表；信度；效度；反应度 DOI：10.3969/j.issn.1005-5304.2010.06.007 中图分类号：R259.75 文献标识码：A 文章编号：1005-5304(2010)06-0013-03 LIU Hui-min, LIU Shao-neng, LIU Zhen, et al (Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China) To explore the reliability, validity and reaction degree of patient reported outcome instrument for chronic hepatitis diseases. One hundred and four cases with chronic B hepatitis, chronic C hepatitis, alcoholic liver disease, steatohepatitis and decompensated cirrhosis were included and tested by patient reported outcome instrument for chronic hepatitis diseases and compared with 51 normal people. The reliability, validity and reaction degree were analyzed. The chronic hepatitis patient and normal people, chronic B hepatitis and other patients with liver disease were compared. The total Cronbach’s Alpha of the instrument was 0.915, the total split-half reliability was 0.703, the KMO value was 0.783, Bartlett test value was 1 801.149 (P ＜0.001), factor analysis resulted in 8 factors with eigenvalue ＞ 1, which contributed to 69.636%. The chronic hepatitis patients and normal people, chronic B Hepa