荚果蕨属植物的化学成分和药理活性研究概况_李姝蓓.pdfVIP

• 292 • 现代药物与临床 Drugs Clinic 第 27 卷 第 3 期 2012 年 5 月 荚果蕨属植物的化学成分和药理活性研究概况 * 李姝蓓，张 东，杨 岚 ，杨洪军 中国中医科学院 中药研究所，北京 100700 摘 要：荚果蕨属植物属蕨类球子蕨科，主要化学成分为黄酮类化合物，还含有酚类、香豆素、甾萜类等，药理作用主要有 抗病毒、驱虫、抗菌等活性，本属植物还具有很高的观赏和食用价值。综述了荚果蕨属植物化学成分和药理活性的研究进展， 为进一步开发利用荚果蕨属植物提供参考。 关键词：荚果蕨属；荚果蕨；东方荚果蕨；中华荚果蕨；化学成分；药理活性 中图分类号：R282.71 ；R285.6 文献标志码：A 文章编号：1674 - 5515(2012)03 - 0292 - 05 Research advances in chemical constituents of plants in Matteuccia Todaro and their pharmacological activities LI Shu-bei, ZHANG Dong, YANG Lan, YANG Hong-jun Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China Abstract: To further research and develop the plants in Matteuccia Todaro of fern (Onocleaceae), the chemical constituents of plants in Matteuccia Todaro and their pharmacological activities were reviewed in this paper. The main chemical constituents are flavonoids, phenols, coumarins, sterols, and terpenes, etc. The pharmacological effects are antivirus, antiparasite, and eliminating bacterium, etc. They are also used as ornamental plants and edible wild herbs. The recent research advances in the chemical constituents of the plants in Matteuccia Todaro, such as M . struthiopteris, M . orientalis, and M . intermedia, and their pharmacological activities are reported in this paper, which could provide the references for the further utilization of the plants in Matteuccia Todaro. Key words: Matteuccia Todaro; Matteuccia struthiopteris (L.) Todaro; Matteuccia orientalis (Hook.) Trev.; Matteuccia intermedia C. Chr; chemical constituents; pharmacological activities 荚果蕨属植物为多年生蕨类，主产于北半球温 1.1 黄酮类化合物 [1] 带，我国有 3 种，分布于南岭山脉以北各省区 。 从荚果蕨属植物中分离鉴定了 13 个黄酮类化 我国分布的 3 种荚果蕨属植物为荚果蕨 Matteuccia 合物，见表 1，其中母核结构中具有 6,8-C-二甲