子宫内膜异位症地研究及治疗进展_周莉娜.pdfVIP

北方药学2011 年第8 卷第11 期 ybyx.05316.cn 49 子宫内膜异位症的研究及治疗进展 周莉娜（广东省雷州市妇幼保健院妇产科 湛江 524200） 摘要：目的：探究子宫内膜异位症的研究及治疗进展。方法：对我院45 例子宫内膜异位症患者，随机分为23 例观察组，22 例对 照组，观察组行腹腔镜联合孕三烯酮手术药物联合治疗，对照组行腹腔镜手术治疗，观察对比两组治疗效果。结果：观察组治疗 有效率为68.8%，对照组治疗有效率40.3% ，观察组明显优于对照组。观察组的病情复发率为 13.04%，对照组复发率为31.82%， 观察组病情复发率低于对照组。观察组不良反应小，术后服药出现闭经8 例，停药3 个月后均恢复，无性交痛、无痛经。用药期间 出现2 例轻度肝功能损伤，口服保肝药物之后，复查肝功能均得以恢复。观察组妊娠率71.43% ；对照组妊娠率50%，手术用药后 妊娠率明显高于单纯手术后妊娠率。结论：腹腔镜手术联合孕三烯酮药物治疗子宫内膜异位症效果显著，可以有效的缓解症状， 降低病情复发率，提高患者妊娠受孕率，而且用药不良反应作用小，在临床上值得推广应用。 关键词：子宫内膜异位症 腹腔镜 孕三烯酮 中图分类号：R711.71 文献标识码：B 文章编号：1672-8351（2011）11-0049-02 Abstract ：Objective: To explore the endometriosis research and treatment advances 。 methods: in our hospital 45 cases of endometriosis patients, were randomly divided into 23 cases in observation group, 22 cases in the control group, the observation group treated with laparoscopic combined Gestrinone operation combined drug therapy, the control group treated with laparoscopic operation, observation comparing the two groups of treatment effect. Results: the observation group with a cure rate of 68.8%, the control group was treated with an efficiency of 40.3%, the observation group was better than control group. The observation group was a recurrence rate of 13.04%, compared to the control group the recurrence rate was 31.82%, the observation group relapse rate lower than that of control group. Adverse reaction of observation group, postoperative medication amenorrhea in 8 cases, the drug after 3 months of recovery, clones, make pain without dysmenorrhea. During the medication appears in 2 patients with mild liver function injury, oral medicine, review the liver function were restored. The observation group the pregnancy rate was 71.43%; the control group the pregnancy rate was 50%, operation after administration of pregnancy rate was significant