肝移植后肝功能异常的诊断和内科处理.pdf

第 27 卷 第 4期 大 连 大 学 学 报 Vo.l 27 No. 4 2006年 8 月 JOU RNA L O F DA L IA N UN IVERS ITY A ug. 2006 首届北京地坛感染病学术会议论文 窦晓光, 丁 阳 ( 中国医科大学附属盛京医院 感染科, 辽宁 沈阳 110004) * : , , , . ,. . : ;;; + : R373. 2 1 : A : 2006) D iagnosis and internal m ed icine treatm en t of liver dysfun ction after O rthotop ic liver transplan tation DOU Xiaoguang, DING ang ( Department of InfectiousD isease, ShengjingHospital ofChinaM edicalUniversity, Shengyang 110004, China) A bstract: The liver dysfunction can be found in patients after orthotopic liver transplantation due to the follow ing factors: the relapse of originaldisease, especially hepatitis B and C, new virus infection, chronic rejection, anti re jection drug tox in. The diagnosis is base on detection ofvirus and liver biopsy except liver function tests. The treat ments include anti- virus therapy before orthotopic liver transplantation, prophylaxesvirus infection, monitoring the concentration of antirejection drug and drug selection. K ey w ord s: liver transplantation; hepatic function; dinicaldiagnosis; therapy . , , , HBVHCVEBV,, ., , ,. . 1 1. 1 , . , , 2~ 3 a, , . * : : ( 1961- ), ,, , ,: 第 4 期 窦晓光等: 肝移植 肝功能异常的诊断及内科处理 17 ,,, , 1~ 3. HBV HCV, : ( 1) HBV HCV., HBV HCV,HBV HCV , ; ( 2) HBVHCV; ( 3) HBVHCV. ,HBIG, ,, , HBV DNA HCV [ 1] RNA, . . , ,. ,, , . , Kuffer,,, . , HBsAgHBcAgHCV . 1. 2 ( 1) HBV, ,