非小细胞肺癌患者血浆纤维蛋白原检测临床意义_葛辉.pdf

2009 13 4 Journal of Clinical Medicine in Practice # 15 # 葛 辉, 姜正华, 朱慕云, 黄 谦 ( , , 225001) : ( NSCLC) 55 NSCLC 20 NS CLC ( P 0. 01) , TNM NSCLC ( r = - 0. 37, P 0. 01) NSCLC , ; , NSCLC : ( NSCLC) ; ; : R 73412 : A : 1672O2353( 2009) 04O0015O03 Clinical significance of plasma fibrinogen level detection in nonOsmall cell lung cancer patients GE Hui, JIANG ZhengOhua, ZHU MuO un, Huang Qian ( Dep ar tment of Resp ir atory M ed icine, S uB ei P eop lecs H osp ital, Yangz hou 225001) ABSTRACT: Objective To stud the relationship betw een plasma fibrinogen level on patho- ph siological characteristics and prognosis in patients w ith nonOsmall cell lung cancer. Methods T he plasma levels of fibrinogen w ere detected in fift Ofive patients w ith nonOsmall cell lung cancer and twent normal controls. Results The plasma levels of fibrinogen in patients w ith nonOsmall cell lung cancer were significantl higher than those of normal controls( P 0. 001) . T he plasma levels of fibrinogen in patients w ith nonOsmall cell lung cancer w ere not related to histological classification or POTNM stages. T he plasma levels of fibrinogen in patients w ith nonOsmall cell lung cancer w ere negativel correlated to the survival span( r = - 0. 37, P 0. 0 1) . Conclusions Elevation of plas- ma levels of fibrinogen ex ists in patients w ith nonOsmall cell lung cancer. T he elevated plasma fib- rinogen level ma be associated with h percoagulabilit state; the plasma levels of fibrinogen w ere negativel correlated to the survival span in patients with nonOsmall cell lung cancer and the w ere important marker of progn