腹泻型肠易激综合征证型及其证候要素的文献的研究.pdfVIP

腹泻型肠易激综合征证型及证候要素的文献研究 沈淑华 黄宣 吕宾 连建伟 王坤根 浙江中医药大学附属第一医院，杭州310006 摘要：目的：探讨腹泻型肠易激综合征(IBS-D)的证型及证候要素的分布规律。方法：采用计算机检索的方法， 检索1989年1月-2012年6月IBS-D的相关文献，建立数据库，进行统计分析。结果：检索出合格文献40篇。IBS-D累积 频率达90％的证型依次是：肝郁脾虚证、脾气虚证、肝旺脾虚证、肝郁气滞证、脾肾阳虚证、脾虚湿盛证、大肠湿热证 和肾阳虚证；累积频率达90％的病位证素依次是脾、肝和肾；累积频率达90％的病性证候要素依次是气虚、气郁、阳 虚和湿阻。结论：基于证型与证候要素的文献研究提示肝脾不和是IBS-D的基本发病环节。 关键词：腹泻型肠易激综合征；证候；证候要素；文献 Literaturestudyofcommonsyndromesandsyndromefactorsofdiarrhea-predominant irritablebowelsyndrome SHENShu-huaHUANG XuanLVBinLIANJian-weiWANGKun-gen TheFirstAffiliatedHospitalofZhejiangChineseMedicineUniversity,Hangzhou310006,China Abstract:Objective:Toinvestigatethedistributioncharacteristicsofsyndromesandsyndromefactorsofdiarrhea- predominantirritablebowelsyndrome(IBS-D).Methods:TheliteraturewasselectedfromJanuary1989toJune2012through computer-basedretrieval,andthenadatabasewasestablishedandanalyzedstatistically.Results:Thecommonsyndromesof IBS-Dwere:liver-stagnationandspleen-deficiencysyndrome,spleen-qideficiencysyndrome,liverexcessandspleendeficiency syndrome,liverdepressionandqistagnationsyndrome,spleenyang-deficiencyandkidneyyang-deficiencysyndrome,spleen-qi deficiencyanddampnessaccumulationsyndrome,largeintestinedampness-heatsyndromeandkidneyyang-deficiencysyndrome. Theaccumulatingrateofthemaindiseaselocationfactorswerespleen,liverandkidneywhichaccountedto90％,whilethe accumulatingrateofthesyndromefactorswereqideficiency,qistagnation,yangdeficiencyanddampnesswhichaccountedto 90％.Conclusion:ThebasicpathogenesisofIBS-Dwasdisharmonybetweenliverandspleen. Keywords:Diarrhea-predominantirritablebowelsyndrome;Syndrome;Syndromefactor;Literature 中华中医药杂志(原中国医药学报)2013年5月第28卷第5期CJTCMP，May2013，V01．28，No．5 ·1539· 证型主要有8种，依次是肝郁脾虚证(25．85％)、脾气虚证 证论治”或“证候”等；英文检索策略：“diarrhea．predominant bowel irritables