局部晚期乳腺癌的治疗体会.pdfVIP

2011 10 19 10 MODERN ONCOLOGY ，Oct. 2011，VOI. 19 ，NO. 10 ·1995 · 现代肿瘤医学 年 月 第 卷第 期 局部晚期乳腺癌的治疗体会 ， ， ， 邱献华 胡建民 贾海全 魏 娅 The treatment experience of locally advanced breast cancer QIU Xianhua ，HU Jianmin ，JIA Haiquan ，WEI Ya Dep artment of Breast ，Tumor Hosp ital of Anyang City ，Henan Anyang 455000 ，China． 【Abstract 】 Objective :To analyze the effect of 85 cases of stage III breast cancer． Methods :From June 2003 to December 2005 ，85 patients with operable stage III breast cancer received surgical operation． They were divided into two groups according to treatment． Operation group (n = 4 1)and preoperative neoadjuvant chemotherapy group (n = 44 )． The operative quality and curative outcome were compared between these groups． Results :The disease free sur- vival time of neoadjuvant chemotherapy group was 59 ． 4 months which was obviously longer than that of operation group 43． 1 months (P ＜ 0 ． 05)． The 5 － year disease free survival rate of the patients with neoadjuvant chemotherapy was 36． 16% ，which was little higher than (34 ． 14 % )the patients of operation group (P ＞ 0 ． 05)． Conclusion :Com- pared with operation group ，neoadjuvant chemotherapy can obviously improve DFS time in patients with operable local- ly advanced breast cancer． 【Key words 】breast cancer ;locally advanced ;neoadjuvant chemotherapy Modern Oncology 2011，19 (10):1995 － 1996 【 】 : 85 III ， 。 :2003 6 2005 摘要 目的 观察 例 期乳腺癌患者治疗的疗效 寻找提高疗效的策略 方法 年 月至 年 12 85 III ， (4 1 ) 月 例 期乳腺癌患者接受了外科手术治疗 根据是否接受新辅助化疗分为手术组 例 和新辅助化