氯诺昔康切口浸润用于术后镇痛临床观察.pdfVIP

250 JBengbuMedCoil，March2011，Vo1．36，No．3 [文章编号]1000-2200(2011)0343250-03 ·临床 医学 · 氯诺昔康切 口浸润用于术后镇痛临床观察 李晓红，金 钟 [摘要]目的：评价氯诺昔康切口浸润用于术后镇痛的可行性及临床效果。方法：选择头颈部手术患者45例，要求术后镇痛者 5例 (C组)，其余随机分为A组和B组，每组20例。A组：氯诺昔康8mg溶于0．9％生理盐水2Oml，切口缝合前，由术者注射 于切口内各层组织；B组：无特殊处理，直接缝合切口；C组：氯诺昔康48mg复合舒芬太尼 100I*g加0．9％生理盐水至 100ml， 术后患者 自控静脉镇痛。分别记录各组术后即刻、术后 1、6、12、24h的疼痛评分，观察药物相关副作用、切 口愈合情况及患者 满意度。结果：A、C组术后各时点疼痛程度明显轻于B组 (P0．01)，C组 1例发生术后呕吐。3组切31均一期愈合。3组满 意度调查均为十分满意或满意。结论：氯诺昔康切31浸润镇痛效果好，简单易行，可用于浅表小切 口手术的术后镇痛。 [关键词]镇痛药 ；氯诺昔康 ；浸润切13 [中国图书资料分类法分类号】R971．1 [文献标识码]A Clinicalobservationofpostoperativeanalgesiabyincisionalinfiltrationoflornoxicam LIXiao—hnag，JINZhong (DepartmentofAnesthesiology，TheFirstAffiliatedHospitalofBengbuMedicalCollege，BengbuAnhui233004，China) [Abstract]Objective：Toevaluatethefeasibilityandclinicalresultsofpostoperativeanalgesiabyincisionalinfiltrationoflomoxicam． Methods：Fony—fivepatientswithheadandnecksurgerywerechosen．Fivepatientsrequiredpostoperativeanalgesiaandtheremaining were dividedintogroupA andgroupB with20caseseach．GroupA：8mglornoxicam dissolvedin0．9％ 20mlnormal saline。before suture，patientswereinjectedbythelayersoftissuewithintheincision；GroupB：Nospecialtreatment，theincisionwassutureddirectly； GroupC：48 mglornoxicam combinedwith 100 gsufentanildissolved in0．9％ salineto 100 ml，postoperativepatient-controlled intravenousanalgesia．Recordpainscore，drug—relatedsideeffects，woundhealingandpatientsatisfactionimmediately，1，6，12，24hours aftereachoperation．Results：PainscoreofrgoupA，CweresignificantlylighterthanrgoupB(P0．01)，1caseofrgoupC postoperativevomiting．Threewoundswere Ihealed．Threesatisfaction surveysarevery satisfied and satisfied．Conclusions： Lomoxicam promisedagoodanalgesiceffectofinfiltrationandcouldbeusedforsuperficialincisionofrpostoperativeanalgesi