老年高尿酸血症及其伴发疾病临床特点.docVIP

老年高尿酸血症及其伴发疾病临床特点 作者：王晓青 王学宏，崔月丽，冯建民 作者单位：1.山东省青岛疗养院门诊部，山东 青岛 266071;2.中国中医科学院中医门诊部 【摘要】 目的：探讨老年高尿酸血症患者的临床特点。方法：选取≥60岁老年高尿酸血症患者243例为Ⅰ组，60岁以下中青年高尿酸血症患者265例为Ⅱ组，同时设立正常对照组(血尿酸正常老年人)243例为Ⅲ组。采用统一设计的体检表对所有患者病史、生活方式、一般情况及各项检查结果进行记录，并进行各组间的比较。结果：Ⅰ组患者高血压、冠心病、高脂血症、糖尿病及脑卒中的发病率均明显高于Ⅲ组患者(P0.05～0.01);Ⅰ组患者肥胖、痛风性关节炎、痛风结石和肾结石的发生比例明显低于Ⅱ组患者(P均0.01);Ⅰ组患者高血压、冠心病、高脂血症及脑卒中的发病率均显著高于Ⅱ组患者(P0.05～0.01)。结论：如果出现高尿酸血症的临床特点，应进行进一步检查，以早期诊断、治疗，改善预后。 【关键词】 尿酸;痛风;老年人 Clinical character of the aged hyperuricemia/WANG Xiaoqing，WANG Xuehong，CUI Yueli//Chinese Journal of Cardiovascular Rehabilitation Medicine，2009，18(4):378 　　Abstract：Objective:To investigate the clinical character of the aged hyperuricemia.Methods:Select 243 aged patients with hyperuricemia(≥60 years old)asⅠgroup, and 265 hyperuricemia patients below 60 years old as Ⅱgroup, meanwhile establish control group (Ⅲ group, 243 normal aged person). The unified designed examination chart that contain medical history, life style, general state of health and all examination results of all cases was adopted.Results:The incidences of hypertension, coronary heart disease, hyperlipidemia, diabetes mellitus and cerebral apoplexy inⅠgroup were significantly higher than those of Ⅲ group(P0.05～0.01); The incidences of obesty，gouty arthritis， gouty calculi and kidney calculus in Ⅰ group were significantly lower than those of Ⅱ group(P0.05～0.01). The incidences of hypertension, coronary heart disease, hyperlipidemia and cerebral apoplexy inⅠgroup were significantly higher than those of Ⅱ group(P0.05～0.01).Conclusion:If the clinical character of hyperuricemia occur， the further examine must performed for prophase diagnosis, treatment and improve prognosis. 　　Author′s　address：Outpatient Department,Qingdao Sanatorium of Shandong Province,Qingdao,Shandong,266071,China 　　Key words：Uric acid; Gout; The aged 　　尿酸是嘌呤代谢的最终产物，高尿酸血症是一种嘌呤代谢紊乱性疾病。随着经济的迅速发展，人们生活水平不断提高，各种与生活方式有关的疾病也随之增加，高尿酸血症已经成为老年人的常见病[1]。高尿酸血症作为心血管疾病的一个独立危险因素与高血压的关系以