原发及转移性肝癌的伽马刀结合介入治疗疗效分析.pdfVIP

Inner Mongolia M e J 2007 39 3 295 原发及转移性肝癌的刀结合介入治疗疗效分析 , , , , ( 内蒙古医学院附属医院放疗科, 内蒙古 呼和浩特 0 1 0 0 5 0 ) [ ] 目的: 探讨肝动脉介入化疗并栓塞结合 射 适形放射治疗原发和转移性肝癌的疗效方法: 2 0 0 3 年3 月~ 2 0 0 5 年8 月, 2 6 例不能手术的肝癌患者中, 2 0 例先行碘油顺铂明胶海绵等经肝动脉化疗栓 塞1 ~ 3 次后, 再进行 射 适形放疗, 用5 0 %~ 7 0 % 等剂量 包绕计划靶区, 单次剂量为4 0 0 ~ 5 0 0 cGy/ 次, 每周3 次, 共计1 0 ~ 1 2 次, 肿瘤边缘总剂量达4 0 ~ 6 0 Gy; 6 例先行体部伽玛刀放疗, 休息2 ~ 3 周后, 行1 ~ 3 次介入治疗结果: 治疗后3 个月总有效率为8 0 8 % ( 2 1 / 2 6 ) , 6 个月及1 年生存率分别为8 4 6 %( 2 2 / 2 6 ) 5 7 7 %( 1 5 / 2 6 ) , 中位生存时间为8 个月结论: 肝动脉介入化疗并栓塞结合 射 适形放射治疗原发和转 移性肝癌是安全有效的方法 [ ] 肝癌; 介入化疗栓塞; 伽玛刀; 适形放射治疗 [ ] R7 3 5 7 [ ] A [ ] 1 0 0 40 9 5 1 (2 0 0 7 ) 0 30 2 9 50 3 Curative Effect Analysis of - Knife Combine with Interventional T herapy for Primary an Metastatic Iiver Cancer ZHANG Baozhen, SUO Zhiming, YANG Guirong, CHEN Yan, Yu Zhilong (Dep artment of Radiation Oncology , The First Aff iliated H osp ital of Inner Mongolia Medical College, H uhhot 0 1 0 0 5 0 , China) [ Abstract] Objective:To evaluate the reponse an tolerance of patients w ith hepatocellular carcinoma( HCC) treate by - knife conformal ra iotherapy combine w ith transcatheter arteral chemoembolization ( TACE) . Methods: From M arch 2 0 0 3 to August 2 0 0 5 , a total of 2 6 patients w ith HCC w ho cann t be treate by surgery w ere selecte . Tw enty of the 2 6 patients w ere treate w ith TACE firstly, TACE was performe using lipio ol, cisplatin, follow e by gelatin spong cubes, - knife conformal ra iotherapy w as performe after TACE w as given 1 ~ 3 times, 5 0 % ~ 7 0 %iso ose inclu e PTV, osage of 4 0 0 ~ 5 0 0 cGy/ fraction, 3 times one week, a total of 9 ~ 1 2 fractions was use for the patients, the total oses in tumor margins were 4 0 ~ 6 0 Gy. Six of the 2 6 patients w ere treate wit