各型乙型肝炎患者血清sIL2RIFNγ和IL1变化的研究.pdfVIP

·10· 变化的研究 陈焰田德英 同济医科大学附属同济医院(武汉，430030) 摘要 肝炎、慢性重型肝炎和活动性肝硬变患者血清标本各16份，16例健康人血清标本作为正常对照组，采用酶联免疫吸附 and 和IFN一7水平升高(PO．05PO．01 调整血清中细胞因子含量可能有助于乙型肝炎的治疗。 关键词tsIL一2RIFN-7lL一1 乙型肝炎 “‘ the and in on LeVelofsIL一2R，IFN—yIL一1 SeraofVarious Study Hepatitis B． 吼跏y矗拧，了k挖铆f雄g．D印口H晰#，lfD，如，弘如嬲D垃4s嚣．7’D行g∥胁妣以(，行而e妇(w“IIl彻，430030) in AbstractAim：TothelevelofsIL一2R，IFN一7andIL一1 seraofvarious B． Method：Serawere study hepatitis obtainedfrom16 withacute B，chronic Band cirrhosis patients hepatitis hepatitisB，hepatitisgravis posthepatitic respec— sIL一2RandIFN一7weredetectedELISA．IL一1weredetectedMTTmethod．16 donorsservedas tively． by by healthy controls．ResuIts{ThelevelofsIL一2R increasedinseraofacute obviously hepatitis，chronichepatitis，hepatitisgravis and with leverIFN一7 cirrhosis of increasedinseraofacute posthepatiticcomparedcontroUingphase．The hepatitis，hep- atitis and but inchronic ThelevelofIL一1increasedinhadofacute cirrhosis， gravisposthepatitic unchanged hepatitis． inchronic and butincirrhosishadnoobvious hepatitis，decreasedhepatitishepatitic gravis lFN一7andIL一1inseraofvarious substantialrolein ofvarious hepatitismaypIay pathogesis hepatitis． words B Key l 3IL一2RlFN一7 lL一1 Hepatitis 乙型肝炎患者，机体细胞免疫应答是抗病毒、保 的诊断标准。16例健康人作为正常对照组。 护免疫的关键。我们对各型乙型肝炎患者血清sIL一 1．1．2 2R、IFN一7和IL一1水平进行检测，以阐明各型乙型肝 炎患者体内细胞免疫功能状态，并对此