复方绞股蓝胶囊治疗中晚期胃癌的临床疗效观察_尹祥敏.pdfVIP

　　 11 　　　4 　　　　　　　　　　　　　　　V OL.11 　　NO .4 　　　　 　　　　　1999 　　　　　　JOURNA L 　OF 　HEZ E 　MEDICA L 　COL LEGE 　　　　　　1999 ＊ 　　 　　　　　 (药理学教研室　274030 　＊菏泽地区人民医院) 　　　　为了探讨中西药复方制剂复方绞股蓝胶囊治疗中 期胃癌的疗效及机理。　以复方绞 股蓝胶囊治疗125 例中 期胃癌患者, 其中单用复方胶股蓝胶囊62 例(治疗组Ⅰ),复方绞股蓝胶囊配合化疗 63 例(治疗组Ⅱ), 另有60 例单用化疗(对照组), 观察三组的有效率、毒副反应等。　治疗组的有效率和 卡氏评分高于对照组(P0.05 ), 毒副反应发生率低于对照组(P0 .05)。　复方绞股蓝胶囊是一具有 较好发展前景的中西药复方制剂。 　复方胶股蓝胶囊/治疗应用;胃癌/治疗;复方绞股蓝胶囊/副作用 　R735.2 　R282 .71 Study on Therapeutic Effect of Treating Moderate and Advanced State Gastric Cancerby the Compound Ji aogulanCapsules Yin Xiangmin Yu Xinmin 　et al (Dep ar tment of P har macology , Hez e M ed ical College,H eze 274030 ) 　　Abstract:　Objective　T o study the effects and mechanism of com pound j iaog u lan capsule (CJC)combined w it h chemothe apy t eatment.Methods　125 cases of gast ic cance in mode ate and advanced st ate we e t eated by this medicine, 62 of t hem eceived only CJC t eatment (the t he apeutic g oup I);63 w e e t eated wit h bot h CJC and chemot he apy (t he t he apeutic g oup Ⅱ).In addition, 60 gast ic cance patients by chemothe apy alone (the cont ol g oup).Obse ve the esponse ates and to xic side-effect of the th ee g oups.Results　T he esponse ates and ka n of sky scale in the t he apeutic g oups w e e highe than that of the cont ol g oup (P0.05 ).At the same time, the toxic side-effects we e lowe t han t hat of t he cont ol g oup (P0.05 ).Conclusion　Compound J iaog u lan capsules a e a kind of Chinese and weste n medicine compound p epa atio n w ith b illiant p ospect s. 　　Key ords:　compound j iaog u lan capsules/the apeutic use;gast ic cance /the apy ;compound j iaog ulan cap- sules/adve se-effect 　　“ 11 ,4 。48 , [ 1] ”、“” , 4 , 6 , 4 。(2) , , LD50