长春碱_长春新碱提取分离方法研究.pdfVIP

37 9 V o.l 37 N o. 9 2008 9 A pplied Chem ica l Indu stry Sep. 2008 1 2 2 李浩, 李一澍 , 卢国杰 1. , 712082; 2. , 7 10054) : , , LSA 2 1, : , 15 m in 1 000W ) , 1 6. 5 1 , L SA21 , 80% , 3 mL /m in, 78. 4% , 62. 2% , 88. 2% , 85. 8% : ; ; ; : R 927. 2 : A : 167 1- 3206 2008) 09- 0993- 03 Study on the extraction and separation of vinblastine and vincristine 1 2 2 L I H ao , L I Yishu , L U Guoj ie 1. D epa rtm en t of Inform ation Eng ineering, T ibe t Co lleg e for N ationa lities, X ianyang 712082, China; 2. Schoo l of Env ironm en tal Science and Eng ineer ing, Chang an U n iv ers ity, X i an 710054, Ch ina) Abstract:The extract ion and separat ion of v inb last ine and v incrist ine w as studied in th is paper. T he fac to rs affecting the ex tracting y ields such as solvent, the w ay of extract ion, ex tracting tmi e and the rat io o f solid to liqu id have been stud ied. T he expermi ent show s that the opt mi al resu lt o f extract ion is benzene and so lut ion 16. 5) are used in extract ion and u ltrasonic tmi e lasts 15 m in, filtrate is separated by LSA 21 resins, cleaned by 80% alcoho l 3 m L /m in) . In th is w ay the ex traction ratio of v inb lastine w as 78. 4% , and the purification ratio reached 88. 2% . T he ex traction ratio of v incrist ine w as 62. 2% , and the purification ratio reached 85. 8% . Keywords:v inblastine; vincrist ine; ex tract ion m ethod; extract ion ra te , 0. 42%