肺癌纵隔淋巴结转移与预后的关系分析.docVIP

肺癌纵隔淋巴结转移与预后的关系分析 　　作者：刘泗军，龙鸿川，阚奇伟，石勇 作者单位：四川省眉山市人民医院胸心外科，四川 眉山 612100 　　【摘要】目的：研究肺癌中不同形式的纵隔淋巴结转移与预后之间的关系。 方法：收集术后病检证实伴有纵隔淋巴结转移的肺癌病例56例，统计纵隔淋巴结的具体转移情况并分为：(1)隆突下淋巴结转移组与非隆突下淋巴结转移组;(2)跳跃式转移组与非跳跃式转移组;(3)1组淋巴结转移组、2组淋巴结转移组及3组淋巴结转移组。比较各相应组的生存情况。 结果：隆突下淋巴结转移组与非隆突下淋巴结转移组的生存曲线比较，差异无统计学意义(P0.05)。跳跃式转移组生存情况较非跳跃式转移组差(P0.05)。纵膈淋巴结转移组数越多预后越差，尤其是伴有3组以上淋巴结转移的患者预后更差(P0.01)。 结论：肺癌纵隔淋巴结的转移形式与预后相关，跳跃式转移及转移组数多的病例预后更差。 　　【关键词】 肺癌;纵隔淋巴结;转移;预后 　　Relationship between mediastinal lymph node metastasis and prognosis of lung cancer 　　LIU Sijun, LONG Hongchuan, KAN Qiwei, SHI Yong 　　(Department of Cardiothoracic Surgery, People′s Hospital in Meishan City, Meishan 612100, China) 　　[ABSTRACT] Objective: To investigate the relationship between different forms of mediastinal lymph node metastasis and prognosis of lung cancer. Methods： Fifty six lung caner cases, with mediastinal lymph node metastasis confirmed by postoperative pathologic examination, were included. Made a comparison of survival of corresponding groups divided according to the forms of mediastinal lymph node metastasis, namely carinal lymph metastasis group and noncarinal lymph metastasis group, skip metastasis group and nonskip metastasis group and the groups according to the number of metastasis from 1 to 3. Rsults： Comparison of survival curves, between carinal lymph metastasis group and noncarinal lymph metastasis group, showed no significant difference(P0.05). Lifetime of skip metastasis group was significantly longer than nonskip metastasis group(P0.05). The more regional mediastinal lymph node metastasis, the worse the prognosis of lung cancer, especially prognosis of cases with three regional mediastinal lymph node metastasis was the worst(P0.01). Conclusions: Forms of mediastinal lymph node metastasis relates with prognosis of lung cancer, prognosis of cases with skip metastasis or more regional lymph node metastasis is worse. 　　[KEY WORDS] Lung cancer; Mediastinal lymph node; Metastasis;