非霍奇金淋巴瘤的研究进展.pdfVIP

! 620! M ODERN ONCOLOGY, M ar2010, VO I18, NO 0 3 [ 13] A lessand ro S, R onert C, John F. HLA expression in cancer : Im p li therapy or th e treatm ent o patients w ith re ractory m etastat ic m el cation or T - cell b ased mi munotherary [ J] . Imm uno G eneties, anoma [ J]. C lin O nco ,l 2005, 23( 10) : 2346- 2357. 200 1, 53( 4 ): 255- 260. [ 16 ] D avis ID, Ch en Q, M orris L, et al. B lood dend rit ic cells generated [ 14 ] , , , . w ith Flt3 ligand and CD40 ligand prmi e CD8+ T cells e icien tly [ J ]. , in cancer patients[ J] . J Imm unother, 2006, 29 ( 5) : 499 - 5 11. 2006, 6( 26) : 818 - 82 1. [ 17 ] , , , . [ 15 ] Dud ley M E, W und erlich JR, Y ang JC, et al. A dopt ive cell t rans er [ J] . , 2008, 29( 19) : 1820 - 1823. th erapy ollow ing nonm y eloablative bu t lym phodep let ing chem o ( 编校: 王 军) 非霍奇金淋巴瘤的研究进展 李禹兵, 刘延香, 路喻清 Non- Hodgkin s lym phom a resea rch: a review o the litera ture L I Y u - b ing, L IU Y an- x iang, LU Y u - q ing M ed ical C olleg e of Yan an Un iv er sity, Yan an 7 16000, Ch ina. Ab stract N on- hodgkin s lymphoma( NHL ) is no t a sing le disease but a large group o diso rders. L ym phocy tes is a m ajor component o the mi mune system, cancer changed the lo ca l lym pho id tissues. There are still a sma ll pa rt o the pr mi ary res istance to chem otherapy ( re rac to ry) , or short- term to allev iate the recurrence o the d isease, the prog nosis is poor, need to ind new means to contro l the grow th o the tum or. T he latest research a re review ed in th is a rti cle. K ey w ords non- H odgk in lymphom a; h isto log ica l subtype; chem otherapy; hema topo ie tic stem ce ll transplantation; mi muni