_BIS对OSAS患者经鼻清醒盲探气管插管镇静程度的评估.doc

BIS对OSAS患者经鼻清醒盲探气管插管镇静程度的评估 【摘要】 目的探讨脑电双频指数（BIS）评价的可靠性。方法选择例Malampati试验III～IV级的行悬雍垂腭咽成形（uvulopalatopharyngiplastyUPPP）。患者????? 【关键词】 脑电双频指数；；镇静；清醒经鼻盲探气管插管 Evaluate Suitable Sedative Depth of obstructive sleep apnea syndrome for conscious blind nasotracheal intubation by Bispectral index 　　【】To evaluate the relibility of obstructive sleep apnea syndrome （OSAS） patients suitable sedative depth for conscious blind nasotracheal intubation by Bispectral index（BIS）. Methods　 Thirty cases of OSAS patients with Malampati test III～IV,without critical organ parenchymal disease,with Uvulopalatopharyngoplasty (UPPP).The patients were administered fentanyl and midazolam by vein until the score of OAA/S dropped to , then for blind nasotracheal intubation.To record the numbers of BP, MAP, SpO2, BIS and OAA/S before administering drugs,after medication,before intubation and after achieving intubation.Result　The values of BIS dropped with the deepening of sedation,and accorded to the drop of OAA/S,and a significant difference was observed compared with before sedation.Their HR, MAP also dropped with the dropping of OAA/S,and a significant difference was observed compared with before sedation. The values of BIS, HR, MAP of the patitents had a significant ascend after intubation, and a significant difference was observed compared with the score of OAA/S dropped to three, SpO2 of both groups consistently maintained in normal range ,The patitents can tolerance the process of the blind tracheal intubation after a suitable sedation.The patitents had no remembrance in following up of post-operation.Conclusion　BIS was avail to evaluate exactly the depth of sedation.During the sedative depth of three of OAA/S and 76-85 of BIS ,it is suitable for conscious blind nasotracheal intubation to be operated. 【Keyword】Bispectral index;obstructive sleep apnea syndrome （OSAS）; sedation;conscious blind nasotracheal intubation 阻塞性睡眠呼吸暂停综合征（OSAS）是成年患者中常见的疾病，在中年男性和女性中的发病率分别高达4%和2%，其中60~90%的患者合并肥胖，大多还存在颈