《Are bone marrow regenerative cells ideal seed cells for the treatment of cerebral ischemia》.pdfVIP

NEURAL REGENERATION RESEARCH Volume 8, Issue 13, May 2013 doi:10.3969/j.issn.1673-5374.2013.13.005 [; ] Li Y, Hua XM, Hua F, Mao WW, Wan L, Li ST. Are bone marrow regenerative cells ideal seed cells for the treatment of cerebral ischemia? Neural Regen Res. 2013;8(13): 1201- 1209. Are bone marrow regenerative cells ideal seed cells for the treatment of cerebral ischemia?★○ 1 1 2 3 1 1 Yi Li , Xuming Hua , Fang Hua , Wenwei Mao , Liang Wan , Shiting Li 1 Department of Neurosurgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China 2 Department of Emergency Medicine, Brain Research Laboratory, Emory University School of Medicine, Atlanta, GA 30322, USA 3 Laboratory of Microbiology and Biochemical Pharmaceutics, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China Abstract Bone marrow cells for the treatment of ischemic brain injury may depend on the secretion of a large Yi Li★, Master, Attending physician. number of neurotrophic factors. Bone marrow regenerative cells are capable of increasing the secretion of neurotrophic factors. In this study, after tail vein injection of 5-fluorouracil for 7 days, Yi Li and Xuming Hua bone marrow cells and bone marrow regenerative cells were isolated from the tibias and femurs of contributed equally to the manuscript. rats, and then administered intravenously via the tail vein after focal cerebral ischemia.