胎盘和骨髓来源的间充质干细胞生物学特性比较.pdf

维普资讯 中国组织工程研究与临床康复 劈 ，2眷 劈 29 2008—07一l5出版 JournalofClinicalRehabilitativel~ssueEngineeringResearch July15,2008 Vo1．12，No．29 综 述 胎盘和骨髓来源的间充质干细胞生物学特性比较★◆ 卢 遥，解慧琪 Biologicalcharacteristics ofplacenta·derived mesench~malstem cells versusbone marrow ·derived mesench~rmalstem cells LuYao，XieHui-q Abstract：Althoughbonemarrow ishtemainsourceofmesenchymalstem cells．itscontentisquitelow inhumanbonemarrow． DivisionofStem Ce1I Recently，htere havebeen mesenchymal stem cellswhich have characteristicsofstem cells／progenitorcellsareisolated from andTissueEngineer- ing．State KeyLabo- peripheralblood。densebone。cartilage，musclena dsoon．Thecommonfeatureofhtesetissuesishtathteyraeallrfom mesoblastof ratoryofBiotherapy． embryonicdevelopment．Th isindicateshtathtereraemesenchymalstem cellsin山eplacenta．Atpresent．htePercollcontinuous WestChinaHospita1． Sichuan University, densitygradientisolationmehtodisclassicinplacenat—derivedmesenchymal stem cells．Wecallgetmesenchymalstem cellswitIl Chengdu 61OO41． uniform itysizenadhighpurityrfom tissuefluidbvtIlismehtod．Placenat—derivde mesenchymal stem cellsna dbonemarrow—derivde Sichuan Province， mesenchymal stem cellshavesimilra apperanacenad superficiesmraker，mena whileplacenta—derivde mesenchymal stem cells China 12ossesspotencyofmulti—directional differentiationandloW immunogenicity．moreover，htereareconveniencetomakeuseofplacenat LuYa