右美托咪啶与咪唑安定对床旁气管切开时重症患者的影响.pdf

( ) 2011 51 1 Journal of Nanchang University( Medical Science) 2011, Vol. 51 No. 1 65 1a 1b 1b 2 , , , ( 1. a. ; b. , 518035; 2., 330003) : 30 2:, 15 , 2 , 2 amsay (H )(CVP) , ( P 0.05) , H (P 0.01) 6. 7%33. 3%,2 ( P 0.01) amsay CVP (P 0.05 ) , : ; ; ; ; ; : 653 : A : 1000- 2294( 2011) 01- 0065- 03 Effects of Dexmedetomidine and Midazolam in Bedside Tracheotomy in Critically Ill Patients 1a 1b 1b 2 LI MingLi ,FENG ongwen ,WU Ming ,XIA Zhihui ( 1a. D ep artment of Gastr ointest inal S urgery ; 1b. D ep artment of Cr it ical Car e Med icine, the First Af f il iated H osp ital of S hen hen Univ er sity , Shen hen 518035, China; 2. D ep artment of Cr it ical Car e Med icine , the Four th Af f iliated H osp ital of N anchang Univ er sity , N anchang 330003, China) ABSTRACT: Objective To explore the effects of Dexmedetomidine and Midazolam in bedside tracheotomy in critically ill patients. Methods T hirty critically ill patients were randomly as signed to preoperatively receive either Midazolam( control group, n= 15) or Dexmedetomidine( ob servation group,n= 15) . All patients underwent tracheotomy with lidocaine for local anesthesia. The total sedative time,ramsay score,analgesic efficiency, heart rate, central venous pressure and incidence of hypotension were observed postoperatively.Results Compared with control group, the sedative time and heart rate significantly decreased in observation group (P 0. 05 or P 0.01,respectively) .T he incidence of hypotension in observation group was obviously lower than that in