阿尔茨海默病行为和精神症状的治疗.pdf

医药专论 ·综 述· 阿尔茨海默病行为和精神症状的治疗 薛海波，张明园* 200030 (上海交通大学医学院附属精神卫生中心精神科，上海 ) 摘要：长期以来，人们关注的通常是阿尔茨海默病(AD)患者的认知功能，如记忆力、智能和语言能力，而痴呆的行为和 精神症状(BPSD)，即偏执、情绪不稳定、无目的漫游、攻击、破坏和吵闹等行为，往往被忽视。事实上，BPSD决定了患 者、照料者的生活质量，其治疗理应引起高度重视。本文综述BPSD 临床表现、症状评定及药物和心理治疗进展。 关键词：阿尔茨海默病；痴呆的行为和精神症状；药物治疗；心理治疗 404404 R749.16 R971 A 1672-9188 2010 07-0404-06 2 中图分类号： ； 文献标志码： 文章编号： ( ) 0 1 0 V o l . 3 1 Treatment for behavioral and psychiatric symptoms of Alzheimers disease N o . 7 XUE Hai-bo, ZHANG Ming-yuan Department of Psychiatry, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai 200030, China ( ) Abstract: During a long time, most concerns have been attracted over the cognitive function of Alzheimers disease AD patients, such as memory, intelligence and language skills, while the behavioral and psychiatric symptoms of ( ) dementia BPSD are neglected. In fact, BPSD mainly infl uences the quality of life of patients and caregivers. Scholars ( ) should pay a great attention to the treatment of BPSD. This review describes the manifestation, assessment of symptoms and medication and psychotherapy of