舒利迭对哮喘缓解期患儿肺功能影响及安全性评价.pdfVIP

论著 舒利迭对哮喘缓解期患儿肺功能影响及安全性评价 方清 (湖南省岳阳市平江县妇幼保健院儿科 湖南岳阳414500) 【摘要l目的 探讨舒利迭对哮喘缓解期患儿肺功能影响及安全性评价。方法 收集哮喘缓解期惠JL60例和健康儿30倒。哮喘缓解 期患儿治疗前和治疗6个月后采取外周血，留取血清备测皮质醇，检测肺功能和骨密度改变。健AtsL采取外周血，留取血清备测皮质醇，检 测骨密度。结果哮喘缓解期志儿治疗后FEVl／FVc和PEF均高于治疗前，差异有统计学意义。哮喘缓解期患儿治疗后皮质醇和骨密度 与治疗前和健康儿比较，差异无统计学毒义。结论舒利速能改善哮喘缓解期志儿气道高反应性，对肾上腺皮质功能和骨密度未见显著 影响。 【关键词】哮喘 舒利透 肺功能 血皮质醇 膏密度 l中图分类号lR974 【文献标识码lA I文章编号l InfluenceofSeretideto FunctiononAsthmaticChildren Pulmonary inRemissionPeriodand Evaluation Safety influenceofSeretideto functiononasthmaticchildreninremissionperiodand [Abstract]ObjectiveInvestigated pulmonary safety evaluation．MethodsCollected60casesofasthmaticchildreninremissionand30casesofhealthychildren．Peripheralblood period of before to function asthmaticchildreninremissionperiod treal}mentandaftertreatmenttheJuneweretakendet雠t COrtisoi．Lung andbone inasthmaticchildrenin the densityweredetected remissionbeforetreatmentandaftortreatmentJune．Peripheral period takentodetect Asthmaticchildren bloodof childrenwere functionandbonedensityweredetected．Results healthy cortis01．Lung inremissionaftertreatment and thanbeforetreatment．andthedifferencewere period FEVl／FVCPEFwere