参麦注射液调节急性肺损伤血管内皮细胞功能的临床的研究.pdfVIP

The clinical study of the effects of Shenmai injection on regulating acute lung injury in vascular endothelial cell function Speciality: Internal Medicine of TCM Author: Cao bin Tutor: Prof. Han Ning Abstract Objective: This study aimed to investigate shenmai Injection regulation of vascular endothelial cell function in acute lung injury, expectations for the acute lung injury prevention and control to provide a new way and basis. Methods: To establish strict diagnostic criteria, inclusion criteria, exclusion criteria and efficacy observation based on the standard, using a randomized, balanced, the control principle, 80 cases of eligible subjects were randomly divided into A, B two group, 40 cases in each group. The A group was treated with routine Western medicines combined with Shenmai injection group ( referred to as Shenmai group ), giving 5% glucose injection 250ml with Shenmai injection 50ml intravenous infusion, once a day, for the rest of conventional treatment of Western medicine; group B as the conventional treatment of Western medicine group ( referred to as the Western medicine group ), giving the conventional treatment of Western medicine. The above two groups of treatment were 10 to 1 courses of treatment, The before and after treatment in patients with clinical symptoms and laboratory indexes were compared. Results: Compared with the western medicine group, the Shenmai group improved significantly in patients with respiratory rate, blood gas the PaO2, PaCO2, the PaO2 / FiO2 is index, significantly reduced the level of ET-1 , ICAM-l and NO, noninvasive positive pressure average ventilation time was significantly shorter, invasiveThe small number of cases of mech