上海交通大学 上海交大 生物化学 课件 chapter 25 AA.pptVIP

AA in excess of those needed for synthesis cannot be stored，nor are they excreted 来自食物(以及被降解蛋白)的AA, 用于新的蛋白和AA(或其它含氮化合物)的合成. 多余的AA(与糖和脂肪酸不同)既不能储存也不能被排出,而只能作为代谢燃料 surplus AA are used as metabolic fuel The α-amino group is removed, most of them are converted into urea 解决氨基(转氨, 进而合成尿素) resulting carbon skeleton is converted into a major metabolic intermediate: acetyl CoA, acetoacetyl CoA, Pyr, or one of the intermediates of TCA 解决碳骨架(α酮酸转变为糖或脂肪酸代谢的中间物) Ubiquitin泛肽，遍在蛋白质: Damaged or unneeded proteins are marked for destruction by the covalent attachment of chains of a small protein, ubiquitin.