《Effects of Maternal Linseed Oil Supplementation on Metabolic Parameters in Cafeteria Dietinduced Obese Rats》.pdfVIP

298 Biomed Environ Sci, 2015; 28(4): 298-302 Letter to the Editor Effects of Maternal Linseed Oil Supplementation on Metabolic Parameters in Cafeteria Diet-induced Obese Rats* 1 1,# 2 3 BENAISSA Nawel , MERZOUK Hafida , MERZOUK Sid Ahmed , and NARCE Michel Because linseed oil may influence maternal cholesterol and triglycerides and are useful in and fetal metabolisms, we investigated its role in improving insulin sensitivity and treating the modulation of lipid metabolism in cafeteria dyslipidemia. Modification of dietary fat composition diet-induced obese rats and their offspring. Female may influence metabolic disorders associated with Wistar rats were fed control or cafeteria food, obesity. However, although it is well documented which were either supplemented or not that consumption of diets high in n-3 PUFA can supplemented with linseed oil (5%) for 1 month improve metabolic alterations, their beneficial before and during gestation. At parturition, serum effects on maternal and neonate obesity have not and tissue lipids and enzyme activities were yet been elucidated. analyzed. Cafeteria diet induced adverse metabolic Linseed oil, an important source of dietary alterations in both mothers and offspring. Linseed α-linolenic acid (ALA, 1