《Identification of Cinobufagin and Resibufogenin as Inhibitors of Enterovirus 71 Infection》.pdfVIP
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Chem.Res.Chin.Univ.,2014,30(6),953—958
of
of and asInhibitors
Identification Resibufogenin
Cinobufagin
Enterovirus71Infection
CHEN
Jiawenl,XULinl,SUN Huafeil一,MATonghui3,
Shiyan91’。,ZHANG
Chunlail,2+
SU JIANG
Weihen91-2+and
AIDS Molecular
1.National Vaccine。2.Key
EngineeringLaboratoryfor Laboratoryfor
R.China,
Sciences,Jilin 130012,P
MinistryofEducation,SchoolofLife University,Changchun
11
MedicalSciences.DalianMedical 6044,尸R.China
3.CollegeofBasic University,Dalian
Inthis and werefoundtoinhibitenterovirus7 invitro
Abstract Paper,cinobufaginresibufogenin 1(EV71)infection
incell and reduction and
50%inhibitoryconcentrations(IC50)ofcinobufaginresibufoge-
viabilityplaque assays.The
nin themwere
were(10.94士2.36)and(218士31)nmol/L,respectively,the50%cytotoxicconcentrations(CC50)of
was
theanti—EV7l
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