核苷，核苷酸及相关试剂.pdfVIP

中国试剂网 3 . 1 . 1 . 8 Nucleosides, Nucleotides Related Reagents Genetic information is stored in DNA as combinatorial codes and rapid development in studies of DNA. At the current time held in nucleosides and nucleotides, in which form it is passed the draft version in decoding and mapping human genome has from parents to their offspring. Analogs of nucleosides and been almost completed, and the functional analyses of genome nucleotides are used clinically as medicinal agents such as and analyses of “Single Nucleotide Polymorphism” (SNP) are reverse transcriptase inhibitors. Therefore, the preparation being vigorously pursued. Discovery of the RNAi process has and development of these species as effective, selective and facilitated the fast progression of studies of RNA. At the same nontoxic antiviral and antitumor agents has been the subject of time, chemically synthesized oligoDNA and oligoRNA have been intense research. studied as potential antisense DNAs, siRNAs and DNA aptamers; In addition to this, the development of Polymerase Chain as oligonucleotide therapeutic agents, primers for PCR method, Reaction (PCR) methodology has brought a dramatic change and elements of DNA computers. Nucleosides and Their Analogs Nucleosides are glycosylamines made by attaching a and used for the treatment of HIV infection; and Cytosine β-D- nucleobase to a ribose or 2-deoxyribose ring, which can be phos- arabinofuranoside (Cytarabine) approved by the FDA in 1969 and phorylated producing nucleotides. Nucleosides analogues ar